What is Lexapro? Lexapro is a trade name for escitalopram, a selective serotonin reuptake inhibitor used to treat clinical depression, generalized anxiety disorder and a number of brain conditions. It is a highly selective inhibitor of serotonin reuptake. How does Lexapro work? Like all SSRI antidepressants, Lexapro blocks the reuptake of serotonin in the synaptic [...]